Serotonin Release Assay (SRA), LMWH

Test Code
16284


CPT Codes
86022

Preferred Specimen
1 mL frozen serum


Minimum Volume
0.4 mL


Transport Container
Transport tube


Transport Temperature
Frozen


Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 6 months


Methodology
Radiobinding Assay (RBA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Sun-Fri; Report available: 1-2 days


Reference Range
See Laboratory Report


Clinical Significance
Low molecular weight heparin serotonin release assay (LMWH-SRA) assay may be useful for in-vitro investigation of LMWH-induced thrombocytopenia and/or thrombocytopenia with thrombosis syndrome (HIT/HITT).

Note: Patients should not be on ticagrelor (Brilinta) as this may result in a false negative serotonin release assay.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.