FSH (Follicle Stimulating Hormone) and LH (Luteinizing Hormone), Serum

7137

2 mL serum

1 mL for each test

Plastic screw-cap vial

Room temperature

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days

Set up: Daily; Report available: Next day

FSH

Male	1.4-12.8	mIU/mL
Female
Follicular Phase	2.5-10.2	mIU/mL
Mid-Cycle Peak	3.1-17.7	mIU/mL
Luteal Phase	1.5- 9.1	mIU/mL
Postmenopausal	23.0-116.3	mIU/mL

Children (<18 years old): FSH reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, the Quest Diagnostics FSH, Pediatrics assay is recommended (test code 36087).

LH

Male
18-59 Years	1.5-9.3	mIU/mL
≥60 Years	1.6-15.2	mIU/mL
Female
Follicular Phase	1.9-12.5	mIU/mL
Mid-Cycle Peak	8.7-76.3	mIU/mL
Luteal Phase	0.5-16.9	mIU/mL
Postmenopausal	10.0-54.7	mIU/mL

Children (<18 years old): LH reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, the Quest Diagnostics LH, Pediatrics assay is recommended (test code 36086).

FSH and LH are secreted by the anterior pituitary in response to gonadotropin-releasing hormone (GNRH) secreted by the hypothalamus. In both males and females, FSH and LH secretion is regulated by a balance of positive and negative feedback mechanisms involving the hypothalamic-pituitary axis, the reproductive organs, and the pituitary and sex steroid hormones. FSH and LH play a critical role in maintaining the normal function of the male and female reproductive systems. Abnormal FSH levels with corresponding increased or decreased levels of LH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased FSH levels are associated with menopause and primary ovarian hypofunction in females and primary hypogonadism in males. Decreased levels of FSH are associated with primary ovarian hyper-function in females and primary hypergonadism in males. Normal or decreased levels of FSH are associated with polycystic ovary disease in females. In males, LH is also called interstitial cell-stimulating hormone (ICSH). Abnormal LH levels with corresponding increased or decreased levels of FSH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased LH levels are associated with menopause, primary ovarian hypofunction, and polycystic ovary disease in females and primary hypo-gonadism in males. Decreased LH levels are associated with primary ovarian hyperfunction in females and primary hyper-gonadism in males.