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PAX8, IHC with Interpretation
Test Code90174
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block
Other Acceptable Specimens
Minimum: 3 unstained slides, positively charged
Instructions
Please include surgical pathology report.
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Immunohistochemistry
Setup Schedule
Set up: Mon-Fri a.m.; Report available: 3 days
Reference Range
Interpretive report
Clinical Significance
PAX8, a nuclear transcription factor, is expressed, along with PAX2, in renal cell carcinoma but not in urothelial carcinoma (which is positive for uroplakin III and P63). Other uses include detection of metastatic ovarian serous tumors (as opposed to mesothelioma).
Performing Laboratory
Quest Diagnostics Nichols Institute |
14225 Newbrook Drive |
Chantilly, VA 20153 |