Prometheus® Crohn's Prognostic

Test Code

90808

CPT Codes
81599

Includes

ASCA IgA ELISA; ASCA IgG ELISA; Anti-OmpC(a) IgA ELISA; Anti-CBir1(a) ELISA; Anti-I2 ELISA; IFA Perinuclear Pattern; DNAse Sensitivity; R702W [C2104T] Mutations; G908R [G2722C] Mutations; L1007fs [3020insC] Mutations

Preferred Specimen

2 mL serum collected in a red-top tube (no gel) --and-- 2 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

2 mL

Instructions

Specimens must be labeled with patient's name and date of collection. Unlabeled specimens will not be accepted for testing. Serum and EDTA whole blood specimens must be shipped together in the same container. Shipment within 7 days of collection and storage at or below room temp is recommended. Shipping room or refrigerated temperature is acceptable. DO NOT FREEZE SPECIMENS.

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Specimens will be rejected if whole blood and serum are not drawn and received together

Methodology
DNA Probe • Indirect Immunofluorescence Assay • Nucleic Acid Amplification (NAT) • Interpretation • Enzyme-Linked Immunosorbent Assay (ELISA)

Setup Schedule

Set up: Daily; Report available: 7 days

Reference Range

See Laboratory Report

Clinical Significance

This test combines proprietary serologic and genetic (serogenetic) markers in a logistic regression model to provide individualized probabilities for developing disease complications after diagnosis in patients with Crohn's disease. This test may allow physicians to stratify their CD patients according to their risks of developing complications over time and personalize the disease tratment plan for the patients.

Performing Laboratory
Prometheus Laboratories, Inc.
9410 Carroll Park Drive
San Diego, CA 92121

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.