A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
ANCA Screen with MPO and PR3, with Reflex to ANCA Titer
Test Code70159
CPT Codes
86021 (x2), 86036
Includes
ANCA Screen with Reflex to ANCA Titer
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.8 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat p.m.; Report available: 3-5 days
Reference Range
ANCA Screen | Negative |
P-ANCA Titer | <1:20 |
C-ANCA Titer | <1:20 |
Atypical P-ANCA Titer | <1:20 |
Myeloperoxidase Antibody
<1.0 AI | No antibody detected |
≥1.0 AI | Antibody detected |
Proteinase-3 Antibody
<1.0 AI | No antibody detected |
≥1.0 AI | Antibody detected |
Clinical Significance
Testing for anti-neutrophil cytoplasmic antibodies (P-ANCA and/or C-ANCA) has been found to be useful in establishing the diagnosis of suspected vascular diseases, inflammatory bowel disease, as well as other autoimmune diseases.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153