Rheumatoid Arthritis Diagnostic Panel 3, Comprehensive

Test Code

19878

CPT Codes
86200, 86235 (x2), 83520 (x3)

Includes

Rheumatoid Factor (IgA, IgG, IgM)
Cyclic Citrullinated Peptide (CCP) IgG
Sjogren's Antibodies (SS-A, SS-B)

Preferred Specimen

3.5 mL serum collected in each of three separate red-top tubes (no gel)

Patient Preparation
Overnight fasting is preferred

Minimum Volume

1.9 mL (x3)

Transport Container

Plastic screw-cap vial (x3)

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric • Serum separator tube (SST) • Heat treated samples • Lithium and heparin plasma

Methodology
Immunoassay (IA)

Setup Schedule

Set up and Report available: See individual assays

Reference Range

Rheumatoid Factor (IgA)

≤6 Negative

>6 Positive

Rheumatoid Factor (IgG)

≤6 Negative

>6 Positive

Rheumatoid Factor (IgM)

≤6 Negative

>6 Positive

CCP Antibody (IgG)

<20 Negative

20-39 Weak positive

40-59 Moderate Positive

>59 Strong positive

Sjogren's Antibody (SS-A)

<1.0 Negative

Sjogren's Antibody (SS-B)

<1.0 Negative

Clinical Significance

This assay may be useful in supporting or ruling out a diagnosis of rheumatoid arthritis.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.