Ki-67/MART-1, IHC without Interpretation

Test Code

91318

CPT Codes
88342

Preferred Specimen

1 formalin-fixed, paraffin-embedded tissue block

Minimum Volume

1 Block

Other Acceptable Specimens

3 unstained, (+) charged slides, submitted in IHC Specimen Transport Kit

Transport Container

IHC Specimen Transport Kit

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Indefinite
Refrigerated: Indefinite
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received frozen

Methodology
Immunohistochemistry (IHC)

Setup Schedule

Setup: Mon-Fri a.m.; Report available: Next day

Reference Range

See Laboratory Report

Clinical Significance

This two-color combination of the proliferative marker Ki-67 and the melanoma marker MART-1 allows assessment of mitotic activity in melanocytic lesions. This can be helpful in differential diagnosis of atypical nevi as well as a prognostic factor in melanoma.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.