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Beta Melanocyte Stimulating Hormone
Test Code91902
CPT Codes
83520<br /> This test is not available for New York patient testing.
Preferred Specimen
3 mL plasma collected in an EDTA (lavender-top) tube
Patient Preparation
Fasting specimen is preferred. Patient should be free from any medication for 2 days (48 hours).
Minimum Volume
1 mL
Transport Temperature
Frozen
Specimen Stability
Room temperature: Not stable
Refrigerated: 6 hours
Frozen: 90 days
Refrigerated: 6 hours
Frozen: 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Received refrigerated
Methodology
Enzyme Linked Immunosorbent Assay (ELISA) • Extraction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Pan Laboratories. This assay has been validated pursuant to the CLIA regulations. It has not been cleared or approved by the U.S. Food and Drug Administration.
Setup Schedule
Set up: Thurs; Report available: 3-8 days
Reference Range
0-150.0 pg/mL
Clinical Significance
Beta Melanocyte Stimulating Hormone is a 22 amino acid peptide produced from the prohormone, Proopiomelanocorticotropin. One of the fragments of Proopiomelanocorticotropin is b-Lipotropin which is further fragmented to form gamma Lipotropin and beta Endorphin. The gamma Lipotropin is then cleaved to form beta MSH. The major biological property of beta MSH is hyperpigmentation. Beta MSH is the major melanocortin in humans. Beta-Melanocyte Stimulating hormone has been found in high levels in patients with Cushings disease, ectopic ACTH producing tumors and also in some non-endocrine tumors.
Performing Laboratory
Pan Laboratories, LLC
15375 Barranca Pkw, E101
Irvine, CA 92618