| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Cysticercus Antibody (IgG), Western Blot, Serum
Test Code34279
CPT Codes
86682
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric
Methodology
Western Blot (WB)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues, Thurs; Report available: 2-5 days
Reference Range
Negative
Interpretive Criteria
This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia solium, the agent causing cysticercosis. Detection of antibodies to any of 6 specific T. solium glycoprotein bands of molecular weights 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reactivity to the 50 and 42-39 glycoprotein bands may reflect cross-reactive antibodies induced by echinococcosis.
A negative test result does not exclude the diagnosis of neurocysticercosis, particularly if only a single brain lesion is present. The sensitivity increases from 50% or less for a solitary brain cyst to greater than 90% if 3 or more cysts are present.
Interpretive Criteria
| Negative | None of 6 specific bands detected |
| Positive | One or more of 6 specific bands detected |
This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia solium, the agent causing cysticercosis. Detection of antibodies to any of 6 specific T. solium glycoprotein bands of molecular weights 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reactivity to the 50 and 42-39 glycoprotein bands may reflect cross-reactive antibodies induced by echinococcosis.
A negative test result does not exclude the diagnosis of neurocysticercosis, particularly if only a single brain lesion is present. The sensitivity increases from 50% or less for a solitary brain cyst to greater than 90% if 3 or more cysts are present.
Clinical Significance
This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia Solium, the agent causing Cysticerosis. Detection of antibodies to any 6 specific T.solium glycoprotein bands of molecular weight 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reac- tivity to the 50 and 42-39 glycoprotein bands may reflect crossreactive antibodies induced by Echinococcus.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
