InScape® Ki-67, Quantitative IHC without Interpretation

Test Code

16223

CPT Codes
88361

Preferred Specimen

Formalin-fixed, paraffin-embedded tissue block

Other Acceptable Specimens

Minimum: 3 unstained, positively charged slides

Transport Container

IHC Specimen Transport Kit

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable

Methodology
Immunohistochemistry

Setup Schedule

Set up: Mon-Fri; Report available: Next day

Clinical Significance

Staining for Ki-67 can be used to aid in the assessing the proliferative activity of normal and neoplastic tissue. Ki-67 is a proliferation marker that correlates with flow cytometric S-phase. Various published studies have suggested that overexpression of Ki-67 in breast cancer may be an unfavorable prognostic indicator. For other type of tumors, definitive interpretive criteria for Ki-67 expression may vary.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.