Progesterone, IVF (Rapid) [8752X]

Test Code
13252


CPT Codes
84144

Preferred Specimen
1 mL serum collected in a serum separator tube (SST®)


Minimum Volume
0.5 mL


Instructions
DHEA supplementation causes a false elevation of values in this standard immunoassay method for progesterone. Physicians using progesterone levels as a criterion for triggering ovulation in an IVF cycle in patients supplemented with DHEA should assess progesterone levels using a LC/MS/MS Progesterone assay, such as test code 17183 performed at Quest Diagnostics San Juan Capistrano.

Do not order progesterone testing as an add on to a barrier gel specimen older than 72 hours. Progesterone binds to barrier gel causing decreased values.

Note: Do not add on progesterone testing to a barrier gel specimen older than 72 hours.


Transport Container
Plastic screw-cap vial


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 1 year


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum stored on barrier gel for more than 72 hours


Methodology
Immunoassay

Setup Schedule
Set up: Daily; Report available: 1 day


Reference Range
Male <1.4 ng/mL
Female    
  Follicular Phase <1.0 ng/mL
  Luteal Phase 2.6-21.5 ng/mL
  Postmenopausal <0.5 ng/mL
  Pregnancy    
  First Trimester 4.1-34.0 ng/mL
  Second Trimester  24.0-76.0 ng/mL
  Third Trimester 52.0-302.0 ng/mL
Children (<18 years old): Progesterone reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, the Nichols progesterone, LC/MS/MS assay is recommended (order code 17183).


Clinical Significance
Levels increase sharply during the luteal phase of the menstrual cycle. The level increases from 9 to 32 weeks during pregnancy.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.