Transferrin, Carbohydrate-deficient (Alcohol Use)

Test Code

CPT Codes
82373, 84466


Preferred Specimen
1 mL serum

Patient Preparation
Fasting preferred

Minimum Volume
0.5 mL

Serum samples must be fully coagulated, centrifuged within 1 hour of collection, and must not contain any particles or traces of fibrin after centrifugation. Transfer serum to a clean, plastic, screw-cap vial.

Transport Container
Plastic screw-cap vial

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric


Setup Schedule
Set up: Mon-Sat p.m.; Report available: Next day

Reference Range
CDT 28.1-76.0 mg/L
Transferrin 188-341 mg/dL
% CDT <2.5 %

Clinical Significance
Heavy alcohol use (defined as >4 or 5 beverages per day for two weeks or more) is commonly associated with elevated CDT levels as are certain liver diseases such as primary biliary cirrhosis and chronic active hepatitis and in some patients with genetic D variants of transferrin.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.