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Sensory Neuropathy Antibody Panel (Ganglioside)
Test Code90124
CPT Codes
83520 (x3)
Includes
Ganglioside GD1b Antibody (IgG), EIA; Ganglioside GD1b Antibody (IgM), EIA; Ganglioside GQ1b Antibody (IgG), EIA
Preferred Specimen
1 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.6 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 21 days
Refrigerated: 7 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature
Methodology
Immunoassay (IA)
Setup Schedule
Set up and Report available: See individual assays
Reference Range
GD1b Ab (IgG) | <1:100 Titer |
GD1b Ab (IgM) | ≤1:800 Titer |
GQ1b Ab (IgG) | <1:100 Titer |
Clinical Significance
Gangliosides GD1b IgG is associated with acute motor and sensory axonal neuropathy with associated cerebellar ataxia and ataxic presentations of Guillain-Barré Syndrome. GQ1b IgG may be associated with Miller-Fisher Syndrome. GQ1b IgM antibody is associated with chronic sensory ataxic neuropathy.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |