Sensory Neuropathy Antibody Panel (Ganglioside)

Test Code

90124

CPT Codes
83520 (x3)

Includes

Ganglioside GD1b Antibody (IgG), EIA; Ganglioside GD1b Antibody (IgM), EIA; Ganglioside GQ1b Antibody (IgG), EIA

Preferred Specimen

1 mL serum

Patient Preparation
Overnight fasting is preferred

Minimum Volume

0.6 mL

Transport Container

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Monday, Wednesday Night; Report available: 2 days

Reference Range

GD1b Ab (IgG)	<1:100 Titer
GD1b Ab (IgM)	≤1:800 Titer
GQ1b Ab (IgG)	<1:100 Titer

Clinical Significance

Gangliosides GD1b IgG is associated with acute motor and sensory axonal neuropathy with associated cerebellar ataxia and ataxic presentations of Guillain-Barré Syndrome. GQ1b IgG may be associated with Miller-Fisher Syndrome. GQ1b IgM antibody is associated with chronic sensory ataxic neuropathy.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.