Saccharomyces cerevisiae Antibodies (ASCA) (IgG, IgA)

Test Code

17609

CPT Codes
86671 (x2)

Preferred Specimen

2 mL serum

Minimum Volume

0.6 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 14 days
Refrigerated: 21 days
Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Lipemia

Methodology
Immunoassay (IA)

Setup Schedule

Tuesday-Saturday Morning Report available: Next Day

Reference Range

Saccharomyces cerevisiae Ab (ASCA) (IgG)

≤20.0 U	Negative
20.1-29.9 U	Equivocal
≥30.0 U	Positive

Saccharomyces cerevisiae Ab (ASCA) (IgA)

≤20.0 U	Negative
20.1-24.9 U	Equivocal
≥25.0 U	Positive

Clinical Significance

Antibodies to Saccharomyces cerevisiae are found in approximately 75% of patients with Crohn's disease, 15% of patients with ulcerative colitis, and 5% of the healthy population. High titers of antibody increase the likelihood of disease, specifically Crohn's disease, and are associated with more aggressive disease.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.