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Saccharomyces cerevisiae Antibodies (ASCA) (IgG, IgA)
Test Code17609
CPT Codes
86671 (x2)
Preferred Specimen
2 mL serum
Minimum Volume
0.6 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 21 days
Refrigerated: 21 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia
Methodology
Immunoassay (IA)
Setup Schedule
Tuesday-Saturday Morning Report available: Next Day
Reference Range
Saccharomyces cerevisiae Ab (ASCA) (IgG)
Saccharomyces cerevisiae Ab (ASCA) (IgA)
≤20.0 U | Negative |
20.1-29.9 U | Equivocal |
≥30.0 U | Positive |
Saccharomyces cerevisiae Ab (ASCA) (IgA)
≤20.0 U | Negative |
20.1-24.9 U | Equivocal |
≥25.0 U | Positive |
Clinical Significance
Antibodies to Saccharomyces cerevisiae are found in approximately 75% of patients with Crohn's disease, 15% of patients with ulcerative colitis, and 5% of the healthy population. High titers of antibody increase the likelihood of disease, specifically Crohn's disease, and are associated with more aggressive disease.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153