Ganglioside GM-1 Antibodies (IgG, IgM), EIA

Test Code
37093


CPT Codes
83520 (x2)

Includes
Ganglioside Antibody IgG and IgM


Preferred Specimen
1 mL serum


Patient Preparation
Overnight fasting is preferred

Minimum Volume
0.2 mL


Transport Container
Plastic screw-cap vial


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature


Methodology
Immunoassay (IA)

Setup Schedule
Set up: Mon, Wed night; Report available: 9 days


Reference Range
GM-1 Antibody (IgG) <1:800 titer
GM-1 Antibody (IgM) <1:800 titer

IgG, IgM Antibodies to Ganglioside GM1
Normal <1:800
Moderately elevated 1:800-1:3200
Highly elevated ≥1:6400


Clinical Significance
Ganglioside GM-1 Antibody IgG is associated with the Guillain-Barre syndrome, particularly the acute motor axonal neuropathy variant. Antibody IgM is associated with chronic multifocal motor neuropathy.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.