IgA

Test Code
539


CPT Codes
82784

Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 90 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly lipemic


Methodology
Immunoturbidimetric

Setup Schedule
Set up: Mon-Fri; Report available: 1-5 days


Limitations
IgA-deficient individuals may have circulating IgA antibodies that can mediate fatal anaphylactoid reactions if IgA is infused or transfused. The absence IgA antibodies does not necessarily indicate the patient may not suffer anaphalaxis because pre-existing antibodies to other serum proteins may exist and cause anaphalaxis.


Reference Range
Cord BloodNot Established
≤3 months5-40 mg/dL
4-6 months7-47 mg/dL
7-11 months12-53 mg/dL
1 year20-73 mg/dL
2 years20-99 mg/dL
3-5 years22-140 mg/dL
6-8 years31-180 mg/dL
9-11 years33-200 mg/dL
12-16 years36-220 mg/dL
17-60 years47-310 mg/dL
≥61 years70-320 mg/dL


Clinical Significance
Increased IgA is associated with monoclonal IgA myeloma, respiratory and gastrointestinal infections, and malabsorption; decreased IgA is found in selective IgA deficiency and in ataxia telangiectasia.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.