Ashkenazi Jewish Panel (4 Tests)

Test Code

90994

CPT Codes
81200, 81220, 81255, 81260

Includes

Cystic Fibrosis, Tay-Sachs DNA, Canavan Disease, Familial Dysautonomia

Preferred Specimen

5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

3 mL

Other Acceptable Specimens

Whole blood collected in: EDTA (royal blue-top), or ACD solution A or B (yellow-top), or sodium or lithium heparin (green-top) tube

Instructions

CF Method: PCR and Allelic discrimination using an oligonucleotide-ligation (OLA) assay.

Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship at room temperature immediately. Do not freeze.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable

Methodology
Multiplex PCR • Massively Parallel Sequencing • Polymerase Chain Reaction (PCR) • Next Generation Sequencing

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon, Sat; Report Available: 11-17 days

Reference Range

See Laboratory Report

Clinical Significance

This panel consists of the diseases frequent in the Ashkenazi Jewish population that have been recommended for population based carrier screening by the Americal College of Obstetricians and Gynecologists (ACOG) and the American College of Medical Genetics. This panel screens for Cystic Fibrosis, Tay-Sachs (DNA), Canavan Disease, and Familial Dysautonomia.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.