MUM1, IHC without Interpretation

Test Code

16258

CPT Codes
88342-TC

Preferred Specimen

Formalin-fixed, paraffin-embedded tissue block

Other Acceptable Specimens

Minimum: 3 unstained, positively charged slides

Instructions

Please include surgical pathology report.

Transport Container

IHC specimen transport kit

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received frozen • Specimens other than paraffin block or slides

Methodology
Immunohistochemical Stain

Setup Schedule

Set up: Mon-Fri; Report available: Next day

Reference Range

See Laboratory Report

Clinical Significance

Multiple myeloma oncogene-1 (MUM1) is a 50 kDa protein encoded by the MUM1 gene. IRF4/MUM-1 is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B cells located in the light zone. This assay identifies MUM1 protein in centrocytes and their progeny, plasma cells, activated T cells, and a wide spectrum of hematolymphoid neoplasms derived from these cells. Therefore, this assay can be used as a powerful tool for the identification and the sub classification of lymphoid malignancies.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.