Multiple Sclerosis Panel 1

Test Code

37581

CPT Codes
82040, 82042, 82784 (x2), 83916

Includes

Oligoclonal Bands (IgG), CSF and IgG Synthesis Rate/Index, CSF

Preferred Specimen

3 mL CSF and 2 mL serum

Minimum Volume

1.5 mL CSF and 1 mL serum

Instructions

Please see the individual tests for specific specimen requirements and stabilities.

Both CSF & serum are required specimens. It is preferred that the collection date and time be the same for both; however, it is acceptable for them to be drawn within 48 hours of each other. If no serum is supplied, the client will be contacted to confirm the order.

CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.

Transport Temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.

Transport Container

Plastic screw-cap vial(s)

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 8 hours
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature • Xanthochromia • RBCs • Hemolysis in CSF

Methodology
Isoelectric Focusing (IFE) • Nephelometry

Setup Schedule

Set up: Mon-Sat; Report available: 2-6 days

Reference Range

See Laboratory Report

Clinical Significance

Useful in the diagnosis of Multiple Sclerosis.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.