Interleukin-2 Receptor Alpha Chain (IL-2Ra/CD25), Soluble

Test Code
34298


CPT Codes
83520

Preferred Specimen
1 mL frozen serum collected in a red-top tube (no gel)


Patient Preparation
No biotin supplements 48 hours prior to blood draw.

Minimum Volume
0.5 mL


Instructions
IL-2R levels may demonstrate diurnal variation. Recommend IL-2R levels be determined at the same time of day for improved longitudinal comparison.


Transport Temperature
Frozen


Specimen Stability
Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST) • Plasma


Methodology
Immunoassay (IA)

FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Setup Schedule
Set up: Wed; Report available: 2-10 days


Reference Range
532-1891 pg/mL


Clinical Significance
Following stimulation by antigen, IL-2R is expressed on all T cells. IL-2R is released by activated cells into the surrounding extracellular fluid. IL2-R is involved in infectious, inflammatory and autoimmune diseases, cancer, and transplantation. IL-2R Antibodies are used therapeutically.
Cytokine levels may demonstrate diurnal variation. Recommend cytokine levels be determined at the same time of day for improved longitudinal comparison.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.