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bcl-2, IHC with Interpretation [39584X]
Test Code39584
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin embedded tissue block submitted in IHC specimen transport kit
Other Acceptable Specimens
3 unstained, positively charged slides
Instructions
Please include surgical pathology report.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Immunohistochemical Assay
Setup Schedule
Set up: Mon-Fri; Report available: 2 days
Reference Range
Interpretive report
Clinical Significance
To help with the diagnosis of lymphomas of follicular cell origin, in paraffin embedded tissues. About 90% of follicular lymphomas have a translocation that juxtaposes the bcl-2 gene to an immunoglobulin gene with subsequent deregulation of protein synthesis and cell proliferation.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153