Prostaglandin E2, Serum/Plasma

Test Code

91901

CPT Codes
84150

Preferred Specimen

3 mL plasma collected in an EDTA (lavender-top) tube

Minimum Volume

1 mL

Other Acceptable Specimens

Serum collected in a red-top tube (no gel)

Transport Temperature

Frozen

Specimen Stability

Room temperature: Not stable
Refrigerated: 24 hours
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature • Received refrigerated • Gross hemolysis • Serum separator tubes (SST)

Methodology
Enzyme Linked Immunosorbent Assay (ELISA) • Extraction

FDA Status
The performance characteristics of this test were determined by Pan Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration.

Setup Schedule

Set up: Tues; Report available: 3-8 days

Reference Range

200-400 pg/mL

Clinical Significance

Prostaglandins are synthesized from arachidonic acid by cyclooxygenase (COX)-1 or -2, which converts the acid into PGH2. This is further processed by cytosolic or microsomal prostaglandin synthesis to become prostaglandin E2. PG E2 is produced in many tissues and the level is increased during inflammation, arthritis, fever, endometriosis, tissue injury, pheochromocytoma, VIP producing tumors and variety of cancers with amine peptide productions. Prostaglandin E2 production and circulating levels are reduced by aspiring and indomethacin treatment.

Performing Laboratory
Pan Laboratories, LLC
15375 Barranca Pkw, E101
Irvine, CA 92618

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.