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Anti-PM/Scl-100 Ab (RDL)
Test Code94646
CPT Codes
86235
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Instructions
(Note: The minimum volume does not allow for repeat testing.) Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Transport Container
Plastic transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 60 days
Refrigerated: 14 days
Frozen: 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Bacterial contamination • Lipemic • Icteric • Non-serum specimen types
Methodology
Enzyme Linked Immunosorbent Assay (ELISA)
Setup Schedule
Set up: Varies; Report available: 14-21 days
Reference Range
<20 Units
Clinical Significance
The anti-PM/Scl-100 antibody is associated with younger age, calcinosis and has lower rates of gastrointestinal symptoms, ILD and pulmonary hypertension. There is also evidence of a possibly better survival compared to the presence of either anti-PM/Scl-75 or anti-Scl-70 antibodies.
Performing Laboratory
Esoterix Inc.
4301 Lost Hills Road
Calabasas, CA 91301-5358