Anti-PM/Scl-100 Ab (RDL)

Test Code
94646


CPT Codes
86235

Preferred Specimen
1 mL serum


Minimum Volume
0.3 mL


Instructions
(Note: The minimum volume does not allow for repeat testing.) Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.


Transport Container
Plastic transport tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 60 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Bacterial contamination • Lipemic • Icteric • Non-serum specimen types


Methodology
Enzyme Linked Immunosorbent Assay (ELISA)

Setup Schedule
Set up: Varies; Report available: 14-21 days


Reference Range
<20 Units


Clinical Significance
The anti-PM/Scl-100 antibody is associated with younger age, calcinosis and has lower rates of gastrointestinal symptoms, ILD and pulmonary hypertension. There is also evidence of a possibly better survival compared to the presence of either anti-PM/Scl-75 or anti-Scl-70 antibodies.


Performing Laboratory
Esoterix Inc.
4301 Lost Hills Road
Calabasas, CA 91301-5358



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.