A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Lipase
Test Code606
CPT Codes
83690
Preferred Specimen
1 mL serum collected in a serum separator tube (SST)
Patient Preparation
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been... determined to interfere with assays for...lipase" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.
Minimum Volume
0.5 mL
Instructions
Note: N-acetyl-p-benzoquinone imine (NAPQI) (metabolite of Acetaminophen) will generate erroneously low results in samples for patients that have taken toxic doses of acetaminophen. (notice FA-000053)
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 8 days
Refrigerated: 8 days
Frozen: 31 days
Refrigerated: 8 days
Frozen: 31 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly icteric
Methodology
Spectrophotometry (SP)
Setup Schedule
Set up: Daily; Report available: Next day
Reference Range
7-60 U/L
Clinical Significance
Confirmatory evidence for diagnosis of pancreatitis.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153