| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Heparin Anti-Xa
Test Code30292
CPT Codes
85520
Preferred Specimen
2 mL frozen platelet-poor plasma collected in 3.2% sodium citrate (light blue-top) tube
Minimum Volume
1 mL
Instructions
Platelet Poor Plasma: Centrifuge light blue-top tube 15 minutes at approx. 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice.
Transport Container
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days
Refrigerated: Unacceptable
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Received room temperature • Received refrigerated
Methodology
Chromogenic Assay
Setup Schedule
Set up: Mon-Sat; Report available: Next day
Reference Range
| UFH Therapeutic Range | 0.30-0.70 IU/mL |
LMWH Therapeutic Ranges (target anti-Xa levels measured 4 hours after dosing):
| Enoxaparin (Lovenox) | |
| Therapeutic bid dosing | 0.6-1.0 IU/mL |
| Therapeutic qD dosing | >1.0 IU/mL |
| Tinzaparin (Innohep) | |
| Therapeutic qD | 0.85 IU/mL |
| Dalteparin (Fragmin) | |
| Therapeutic qD | 1.05 IU/mL |
For more information on this test, go to: http://education.questdiagnostics.com/faq/FAQ53v1 (This link is being provided for informational/ educational purposes only.)
Clinical Significance
This assay is useful in measuring heparin concentration in patients treated with low molecular weight heparins (i.e. Enoxaparin/Lovenox) or unfractionated heparin. It is not intended for measurement of Rivaroxaban (Xarelto) or Fondaparinux (Arixtra).
Refer to test code 90981 for Rivaroxaban measurement and test code 16103 for Fondaparinux measurement.
Refer to test code 90981 for Rivaroxaban measurement and test code 16103 for Fondaparinux measurement.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
