Hepatitis C Antibody with Reflex to HCV RNA,PCR w/Reflex to Genotype, LiPA

Test Code

94345

CPT Codes
86803

Includes

If Hepatitis C Antibody is reactive or borderline, then Hepatitis C Viral RNA, Quantitative, Real-Time PCR will be performed at an additional charge (CPT code(s): 87522).
If Hepatitis C Viral RNA, Quantitative, Real-Time PCR is ≥300 IU/mL, then Hepatitis C Viral RNA Genotype, LiPA will be performed at an additional charge (CPT code(s): 87902).

Preferred Specimen

2.5 mL serum collected in two serum separator tubes (SST)

Minimum Volume

2 mL (x2)

Other Acceptable Specimens

Plasma collected in two EDTA (lavender-top) tubes

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Red-top tube (no gel) • Heparinized plasma

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Mon-Sat; Report available: 1- 5 days (5 days if all 3 tests are done)

Reference Range

Non-Reactive

Clinical Significance

Hepatitis C Virus (HCV) is the major cause of hepatitis. Making positive HCV Ab tests reflex to confirmatory molecular testing is necessary to confirm active HCV infection. Providing a second reflex to perform genotyping on HCV isolates when RNA is detected is also a necessary step before starting therapy. This double reflex will reduce the percentage of antibody-positive patients who lack appropriate confirmatory RNA testing and who do not have genotype testing performed.

Performing Laboratory
Quest Diagnostics Nichols Institute Chantilly
14225 Newbrook Dr
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.