A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Factor XI Mutation Analysis (Ashkenazi-Jewish)
Test Code16023
CPT Codes
81401
Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
3 mL
Other Acceptable Specimens
Whole blood collected in an ACD (yellow-top) tube, or sodium heparin (green-top) tube
Instructions
Specimen stability is crucial. Store and ship room temperature immediately. Do not freeze.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable
Refrigerated: 8 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Do not reject
Methodology
Polymerase Chain Reaction (PCR) • Single Nucleotide Primer Extension
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Thurs; Report available: 8 days
Limitations
These mutations account for more than 99% of disease causing mutations in the Ashkenazi Jewish population.
Reference Range
See Laboratory Report
Clinical Significance
This test identifies Ashkenazi-Jewish individuals who are at risk of having prolonged bleeding incidents (especially during surgery) due to mutations in the factor XI gene.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |