Imipramine

Test Code

887

CPT Codes
80299

Includes

Imipramine, Desipramine and Total

Preferred Specimen

3 mL serum collected in a red-top tube (no gel)

Minimum Volume

1.5 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top), sodium heparin (green-top), or lithium heparin (green-top) tube

Instructions

Collect at steady-state trough concentration. Specimen should be collected >12 hours after dose.

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 5 days
Refrigerated: 5 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Gel barrier/Serum separator tube (SST)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat; Report available: 1-2 days

Reference Range

Total

150-250 mcg/L

Clinical Significance

Imipramine is a tricyclic antidepressant drug used to treat depression. Therapeutic drug monitoring is used to optimize dose and to avoid toxicity.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.