Selenium, Blood

Test Code
6296


CPT Codes
84255

Preferred Specimen
2 mL whole blood collected in an EDTA trace metal-free (royal blue-top) tube


Minimum Volume
1 mL


Other Acceptable Specimens
Sodium heparin trace metal-free (green-top) tube


Instructions
Carefully clean skin prior to venipuncture. Avoid worksite collection.

Tests performed on a specimen submitted in a non-trace element tube or non acid washed/non metal free container may not accurately reflect the patient's level. If a non-trace element tube/container is received, it will be accepted for testing. However, elevated results shall be reported with a message that a re-submission with a trace element tube/container is recommended.


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 30 days


Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues, Fri; Report available: 1-5 days


Reference Range
<20 yearsNot established
20-50 years115-240 mcg/L
>50 years100-250 mcg/L


Clinical Significance
Selenium (Se) is a key component of a number of functional selenoproteins required for normal health. The best known of these are the antioxidant glutathione peroxidase enzymes, which remove hydrogen and damaging lipid and phospholipid hydroperoxides generated in vivo by free radicals and other oxygen-derived species. If not removed, lipid hydroperoxides impair membrane structure and function and cause blood-clotting disturbances by decreasing the production of prostacyclin while increasing the production of thromboxane.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.