ER/PR, Paraffin Block [7037X]

Test Code

10694

CPT Codes
88360 (x2)

Preferred Specimen

Formalin-fixed, paraffin embedded tissue block submitted in an IHC Specimen transport kit

Other Acceptable Specimens

Minimum: 5 unstained, positively charged slides

Instructions

Tumor paraffin block (formalin-fixed only) or five 4-micron unstained sections on Poly-L-Lysine or Silane coated slides.

Please submit stained H & E slide and a copy of the pathology report. Ship at room temperature. Do not place paper labels with adhesive backing on slides. Use pencil or xylene resistant pen to write on the frosted end of the slide only.

Please note: Per ASCO/Cap guidelines, ER (Estrogen Receptor) and PR (Progesterone Receptor) positivity requires at least 1% of tumor cells to show positive nuclear staining of any intensity.
A negative result for ER and PR will be reported if < 1% of tumor cells show staining.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received frozen

Methodology
Immunohistochemistry (IHC)

Setup Schedule

Set up: Mon-Fri; Report available: 3 days

Reference Range

Interpretive report

Clinical Significance

Estrogen and progesterone receptor assays are routinely performed on breast carcinomas to assess responsiveness to endocrine therapy and prognosis.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.