Endomysial IgG Antibody Screen and Titer

Test Code

91985

CPT Codes
86231<br /> **This test is not available for New York patient testing**

Includes

Endomysial IgG Titer will report when the titer is ≥2.5 (CPT code(s): 86231)

Preferred Specimen

2 mL frozen serum

Minimum Volume

0.3 mL

Instructions

Allow the blood to clot in an upright position for at least 30 minutes but not longer than 1 hour before centrifugation. Centrifuge for at least 15 minutes at 2200-2500 RPM at ambient temperature within one hour of collection. Store at -20°C and send 2 mL of serum frozen in a plastic vial.

Transport Container

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Lipemia • Microbially contaminated specimens • Specimens received outside of stability

Methodology
Immunofluorescence Assay (IFA)

FDA Status
This test was developed and its performance characteristics determined by BioAgilytix Diagnostics. It has not been cleared or approved by the FDA. BioAgilytix Diagnostics is regulated under CLIA as qualified to perform high complexity testing. This test is used for clinical purposes.

Setup Schedule

Set up: Mon-Fri; Report available: 2 days

Reference Range

Endomysial IgG

Screen Negative

Clinical Significance

Serological methods of detecting Immunoglobulin A (IgA) antibodies to gliadin, endomysium (EMA), reticulin, and tissue transglutaminase are routinely used for diagnosing both symptomatic and asymptomatic patients with Celiac Disease (CD). Since Immunoglobulin A (IgA) deficiency is 10 to 15 times more common in patients with Celiac Disease than in healthy subjects, IgG-specific antibody tests for endomysium are useful for the identification of IgA-deficient patients with CD.

Performing Laboratory
BioAgilytix Diagnostics
1256 Soldiers Field Rd
Brighton, MA 02135

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.