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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Copper, 24-Hour Urine
Test Code365
Quest Code
365
CPT Codes
82525
Includes
CPT code 81050 may be added at an additional charge for volume measurement
Preferred Specimen
7 mL aliquot of a well-mixed 24-hour urine collected in an acid-washed or metal-free container
Minimum Volume
3 mL
Instructions
Collect without preservative and transport in an acid-washed or metal-free plastic container. Record total volume on specimen container and on test requisition. To avoid contamination, do not measure 24-hour volume.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Random urine • Fecal contamination
Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: Next day
Reference Range
15-60 mcg/24 h
Clinical Significance
Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Urinary copper concentrations are also useful to monitor patients on chealation therapy.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153