Legionella pneumophila Antibody (IgG), IFA

Test Code
36580


CPT Codes
86713

Preferred Specimen
1 mL serum


Minimum Volume
0.2 mL


Transport Container
Plastic screw-cap vial


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Methodology
Immunofluorescence Assay (IFA)

Setup Schedule
Set up: Tues-Sat; Report available: 2-4 days


Reference Range
<1:64 titer


Clinical Significance
Legionella infection is associated with 2 clinically and epidemiologically distinct illnesses, Legionnaires' disease and Pontiac fever. Legionnaires' disease is characterized by fever, cough, myalgia, and pneumonia, whereas, Pontiac fever is a milder illness without pneumonia. Inhaling aerosols of water contaminated with Legionella species is believed to be the primary mode of infection; the incubation period is generally 2-10 days. The assays performed detect antibodies to Legionella pneumophila serogroups 1-7. An IgM titer >1:256 provides presumptive evidence of infection at an undetermined time. A 4-fold rise in IgG titer to ≥1:256 between acute and convalescent sera may be used in the laboratory confirmation of Legionella infection with these serogroups of L. pneumophila.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.