Advanced Lipid Panel, Cardio IQ®

Test Code
92145


CPT Codes
80061, 83704, 82172, 83695

Includes
Cardio IQ® Cholesterol, Total; Cardio IQ® HDL Cholesterol; Cardio IQ® Triglycerides; Cardio IQ® Non-HDL and Calculated Components; Cardio IQ® Lipoprotein Fractionation, Ion Mobility; Cardio IQ® Apolipoprotein B; Cardio IQ® Lipoprotein (a)

If Triglyceride is >400 mg/dL, Cardio IQ® Direct LDL will be performed at an additional charge (CPT code: 83721).


Preferred Specimen
4 mL serum


Patient Preparation
If a Cholesterol measurement is to be performed along with Triglycerides, but not part of a Lipid Panel, then the patient should be fasting 9-12 hours prior to collection. If the Cholesterol is ordered as part of a Lipid Panel, then a fasting sample is not required.

Minimum Volume
2 mL


Instructions
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for... Cholesterol, Uric Acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.


Transport Container
Plastic screw-cap vial


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 15 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Moderate to grossly icteric


Methodology
Enzymatic • Spectrophotometric • Ion Mobility • Fixed Rate Nephelometry • Immunoturbidometric • Immunoassay (IA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Mon-Fri; Report available: 4-7 days


Reference Range
See Laboratory Report


Clinical Significance
The advanced lipid profile provides a more comprehensive assessment of dyslipidemia and cardiovascular risk than standard lipid panel measurements.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.