Tyrosinase, IHC with Interpretation

Test Code
90187


CPT Codes
88342

Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block


Other Acceptable Specimens
Minimum: 3 unstained, positively charged slides


Instructions
Please include surgical pathology report.


Transport Container
IHC Specimen Transport Kit


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry

Setup Schedule
Set up: Mon-Fri; Report available: 3 days


Reference Range
Interpretive report


Clinical Significance
Tyrosinase, an enzyme that mediates melanin pigment biosythesis, is immunoreactive in amelanotic and melanotic tumors. Tyrosinase is also one of the common targets of immunoreactive lymphocytes in melanoma.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.