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Tyrosinase, IHC with Interpretation
Test Code90187
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block submitted in an IHC specimen transport kit
Minimum Volume
3 slides
Other Acceptable Specimens
3 unstained, positively (+) charged slides
Instructions
Please include surgical pathology report.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Immunohistochemistry
Setup Schedule
Set up: Mon-Fri; Report available: 3 days
Reference Range
Interpretive report
Clinical Significance
Tyrosinase, an enzyme that mediates melanin pigment biosynthesis, is immunoreactive in amelanotic and melanotic tumors. Tyrosinase is also one of the common targets of immunoreactive lymphocytes in melanoma.
Performing Laboratory
Quest Diagnostics Nichols Institute |
14225 Newbrook Drive |
Chantilly, VA 20153 |