Fungal Panel 3, Immunodiffusion

Test Code

CPT Codes
86606 (x3), 86612, 86628, 86635, 86698

Aspergillus Antibodies, Immunodiffusion
Blastomyces Antibody, Immunodiffusion
Candida Antibody, Immunodiffusion
Coccidioides Antibody (IgG), Immunodiffusion
Histoplasma Antibody, Immunodiffusion

Preferred Specimen
2 mL serum

Minimum Volume
1 mL

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • CSF • Pleural fluid

Immunodiffusion (ID)

Setup Schedule
Set up: Tues-Sat; Report Available: 3-5 days

Reference Range
See Laboratory Report

Clinical Significance
This immunodiffusion assay is highly specific for histoplasmosis infection but may have low sensitivity in early infection. Two different immunoprecipitin bands may be detected. The M band develops with acute infection, is often present in chronic infection, and may persist for months to years. The H band, which is usually present with the M band, generally suggests a chronic or severe acute infection. The presence of both the H and M bands is considered conclusive for the diagnosis of histoplasmosis.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.