Fibrinogen Comprehensive Panel with Consultation

Test Code

CPT Codes
85384, 85385, 85635, 85670

Fibrinogen Activity, Clauss
Fibrinogen Antigen, Nephelometry
Reptilase Clotting Time
Thrombin Clotting Time with Reflex to Mixing Studies
Coagulation Consultation

If the Thrombin Clotting Time is >23 seconds, Mixing Studies will be performed at an additional charge (CPT codes(s): 85675).

Preferred Specimen
1 mL plasma collected in each of four separate 3.2% sodium citrate (light blue-top) tubes

Minimum Volume
1 mL (x4)

Centrifuge light blue-top tube 15 minutes at approximately 1500 x g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into plastic vials. Plasma must be free of platelets (<10,000/mcLl). Freeze immediately and ship on dry ice.

Transport Container
Transport tube(s)

Transport Temperature

Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Clotted

Nephelometric • Clot-Based Assay • Photometric Clot Detection • Clot Detection, Clauss

Setup Schedule
Set up and Report available: See individual tests

Reference Range
See Laboratory Report

Clinical Significance
The Fibrinogen Comprehensive Panel is used in evaluating suspected hypo- or dysfibrinogenemia by determining the conversion rate of fibrinogen to fibrin.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.