Porphobilinogen, Quantitative, Random Urine

Test Code
6329

CPT Codes
84110

Preferred Specimen
10 mL random urine collected in a plastic leak-proof container - protected from light

Minimum Volume
2 mL

Instructions
Do not use preservatives. Optimal pH is 6-7. Wrap sample in aluminum foil to protect from light. Ship frozen or refrigerated (cold packs).

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: Unacceptable
Refrigerated (pH 6-7): 7 days
Frozen (pH 6-7): 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Not protected from light

Methodology
Colorimetric (C)

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues, Thurs, Sat; Report available: 3-6 days

Reference Range
See Laboratory Report

Clinical Significance
Urinary Porphobilinogen is the first step in the diagnosis of acute intermittent porphyria (AIP). AIP is an autosomal dominant disorder characterized by deficiency of porphobilinogen deaminase. An acute attack usually includes gastrointestinal disturbance and neuropsychiatric disorders.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.