Flunitrazepam and Metabolites, Quantitative, Urine

Test Code
18886

CPT Codes
80346

Includes
Flunitrazepam, 7-Aminoflunitrazepam, N-Desmethylflunitrazepam

Preferred Specimen
2 mL unpreserved urine

Minimum Volume
1 mL

Instructions
Do not use any preservative or additives.

Transport Container
Sterile Container, leak-proof

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: Unacceptable
Refrigerated: 14 days
Frozen: 60 days

Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Setup Schedule
Set up: Thurs a.m.; Report available: 4 days

Reference Range
Limit of quantitation
Flunitrazepam  10 ng/mL
7-Aminoflunitrazepam  10 ng/mL
N-Desmethylflunitrazepam  10 ng/mL


Clinical Significance
In Latin America and Europe, Rohypnol (Flunitrazepam) is prescribed as a short-term treatment for insomnia, and as preanesthetic medication.
Flunitrazepam is considered a drug of abuse when used to enhance the effect of other substances such as marijuana, heroin, and ethanol. The combination of ethanol and flunitrazepam may lead to sedation, loss of motor function, impaired judgment, behavioral changes, and anterograde amnesia.

Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.