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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Clomipramine
Test Code30013
CPT Codes
80299
Includes
Clomipramine, Desmethylclomipramine and Total
Preferred Specimen
3 mL serum collected in a red-top tube (no gel)
Patient Preparation
Collect at steady-state trough concentration. Specimen should be collected >12 hours after dose.
Minimum Volume
1.5 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, or lithium heparin (green-top) tube
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 5 days
Frozen: 30 days
Refrigerated: 5 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gel barrier/Serum separator tube (SST)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: Next day
Reference Range
Clomipramine | 50-250 mcg/L |
Desmethylclomipramine | 150-350 mcg/L |
Total | 200-600 mcg/L |
Clinical Significance
Clomipramine and its active metabolite, norclomipramine are antidepressant drugs. Therapeutic drug monitoring is useful to optimize dose and to avoid toxicity.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153