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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Carbapenemase Detection, Phenotypic
Test Code18869
CPT Codes
87184
Preferred Specimen
1 pure isolate of Enterobacteriaceae or Pseudomonas aeruginosa on slant, swab or plate
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Varies with species and transport system
Refrigerated:Varies with species and transport system
Frozen: Unacceptable
Refrigerated:Varies with species and transport system
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Mixed isolates • Organisms other than enterobacteriaceae or pseudomonas aeruginosa • Nonviable organisms
Methodology
Modified Disk Diffusion
Setup Schedule
Set up: Daily; Report available: 3 days
Reference Range
Negative
Clinical Significance
Carbapenemase-producing organisms can be a difficult therapeutic challenge, due to their broad spectrum of resistance to beta-lactams. The profile of carbapenemase beta-lactam resistance is similar to that of extended- spectrum beta-lactamases (ESBLs) with the addition of resistance to the carbapenems (imipenem, meropenem, doripenem, and ertapenem). In addition, carbapenemase producers may be cross-resistant to a wide range of antibiotic classes including the aminoglycosides, fluoroquinolones, and sulfa drugs.
Performing Laboratory
Quest Diagnostics Nichols Institute |
14225 Newbrook Drive |
Chantilly, VA 20153 |