Steroid Panel, PCOS/CAH Differentiation

Test Code
90426

CPT Codes
84403, 84402, 82626, 82157, 83498, 82634

Includes
Testosterone, Total, LC/MS/MS
Testosterone, Free
DHEA, Unconjugated
Androstenedione
17-Hydroxyprogesterone
11-Deoxycortisol

Preferred Specimen
1 mL serum collected in a red-top tube (no gel)

Minimum Volume
0.6 mL

Instructions
Collect specimen in red-top tube (no gel); spin down immediately and pour off into a 13x75 plastic transport tube.

Transport Container
Plastic screw-cap vial

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tubes (SST) • Gross hemolysis • Moderate hemolysis • Gross lipemia • Gross icterus • Plasma

Methodology
Chromatography/Mass Spectrometry • Equilibrium Dialysis

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Sun, Tues; Report available: 5-10 days

Reference Range
See individual tests

Clinical Significance
This panel is important in the differential diagnosis of PCOS vs. non-classical CAH in women with oligomenorrhea/amenorrhea and signs of androgen excess.

Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.