Protein S Antigen, Free

Test Code
10170

CPT Codes
85306

Preferred Specimen
1 mL frozen plasma collected in a 3.2% sodium citrated (light blue-top) tube

Minimum Volume
0.5 mL

Instructions
Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.

Transport Container
Plastic screw-cap vial

Transport Temperature
Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen -20° C: 30 days
Frozen -70° C: 1 year



Methodology
Immunoturbidimetric

Setup Schedule
Set up: Tues-Sat a.m.; Report available: Next day

Limitations
Expected impact by therapeutic levels (potential interference depends upon drug concentration): Warfarin: decrease; Heparin (UFH or LMWH): no effect; Dabigatran or Argatroban (Thrombin Inhibitors): no effect; Rivaroxaban or Apixaban (Factor Xa Inhibitors): no effect.

Reference Range

Male 57-171 % normal
Female 50-147 % normal



Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.