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Yo Antibody Screen with Reflex to Titer and Western Blot
Test Code90119
CPT Codes
86255
Includes
If Yo Antibody Screen, IFA is positive, then Yo Antibody, Western Blot will be performed at an additional charge (CPT code(s): 84181).
If Yo Antibody, Western Blot is positive, then Yo Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
If Yo Antibody, Western Blot is positive, then Yo Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
Preferred Specimen
0.5 mL serum
Patient Preparation
Overnight fasting is preferred
Minimum Volume
0.2 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Methodology
Immunofluorescence Assay (IFA)
FDA Status
This test was developed and its performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
Setup Schedule
Set up: Mon, Wed, Fri a.m.; Report available: 4 days
Reference Range
| Yo Ab Screen, IFA | Negative |
| Yo Ab, Western Blot | Negative |
| Yo Ab Titer | <1:40 Titer |
Clinical Significance
Purkinje Cell (Yo) antibody is found in approximately half of the patients with paraneoplastic cerebellar degeneration and is associated with ovarian, uterine, and small cell lung carcinomas and Hodgkin’s lymphoma.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
