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Testosterone, Free (Dialysis), Total (MS) and Sex Hormone Binding Globulin
Test Code37073
CPT Codes
84403, 84402, 84270
Preferred Specimen
3 mL serum collected in a red-top tube (no-gel)
Minimum Volume
1 mL
Instructions
Specify age and sex on test request form.
Note: Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Note: Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Serum separator tube (SST) • Plasma
Methodology
Chromatography/Mass Spectrometry • Equilibrium Dialysis • Calculation (CALC) • Immunoassay (IA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: 4 days
Reference Range
See Laboratory Report
Clinical Significance
Testosterone circulates almost entirely bound to transport proteins: normally less than 1% is free. Measurement of Free Testosterone may be useful when disturbances in Sex Hormone Binding Globulin (SHBG) are suspected such as when patients are obese or have excessive estrogen. Testosterone measurements are used to assess erectile dysfunction, infertility, gynecomastia, and osteoporosis and to assess hormone replacement therapy.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
