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Propafenone
Test Code6278
CPT Codes
80299
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Draw sample 2-6 hours post oral dose.
Minimum Volume
0.5 mL
Other Acceptable Specimens
Plasma collected in sodium heparin (green-top) tube
Instructions
Collect blood in a plain red-top (no-gel) tube for serum and a sodium heparin (green-top) tube for plasma. Do not use gel barrier tubes.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gel barrier/Serum Separator Tube (SST®)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues, Thurs; Report available: 6 days
Reference Range
0.2-1.6 mcg/mL
Clinical Significance
Propafenone is a cardiac drug for treating ventricular arrhythmias. Therapeutic drug monitoring is important to optimize dose, to assure compliance, and to avoid toxicity.
Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386