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ERG, IHC without Interpretation
Test Code91313
CPT Codes
88342
Preferred Specimen
1 formalin-fixed, paraffin-embedded tissue block
Minimum Volume
1 Block
Other Acceptable Specimens
3 unstained, (+) charged slides, submitted in IHC Specimen Transport Kit
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinite
Refrigerated: Indefinite
Frozen: Unacceptable
Refrigerated: Indefinite
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received frozen
Methodology
Immunohistochemistry (IHC)
Setup Schedule
Setup: Mon-Fri a.m.; Report available: Next day
Reference Range
See Laboratory Report
Clinical Significance
A marker of prostate cancer. Overexpression of ERG protein correlates with TMPRSS2-ERG chromosomal translocation, which are seen in 50-70% of prostate carcinomas. ERG is not expressed in benign prostatic epithelium but can be expressed in PIN. Among other tumor types, ERG is a marker of vascular tumors but is only rarely seen in carcinomas from other tissue sites.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 14225 Newbrook Drive |
| Chantilly, VA 20153 |
