Sensory Neuropathy Antibody Panel (Ganglioside)

Test Code

CPT Codes
83520 (x3)

Ganglioside GD1b Antibody (IgG), EIA; Ganglioside GD1b Antibody (IgM), EIA; Ganglioside GQ1b Antibody (IgG), EIA

Preferred Specimen
1 mL serum

Patient Preparation
Overnight fasting is preferred

Minimum Volume
0.6 mL

Transport Container
Plastic screw-cap vial

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature

Immunoassay (IA)

Setup Schedule
Set up: Monday, Wednesday Night; Report available: 2 days

Reference Range
GD1b Ab (IgG) <1:100 Titer
GD1b Ab (IgM) ≤1:800 Titer
GQ1b Ab (IgG) <1:100 Titer

Clinical Significance
Gangliosides GD1b IgG is associated with acute motor and sensory axonal neuropathy with associated cerebellar ataxia and ataxic presentations of Guillain-Barré Syndrome. GQ1b IgG may be associated with Miller-Fisher Syndrome. GQ1b IgM antibody is associated with chronic sensory ataxic neuropathy.

Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.