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Epstein-Barr Antibody Panel Comprehensive
Test Code91838
CPT Codes
86663, 86664, 86665 (x2)
Includes
Epstein-Barr Virus Viral Capside Antigen (VCA) AB (IgM)
Epstein-Barr Virus, Early Antigen D Antibody (IgG)
Epstein-Barr Virus Nuclear Antigen (EBNA) AB (IgG)
Epstein-Barr Virus Viral Capsid Antigen (VCA) AB (IgG)
Epstein-Barr Virus, Early Antigen D Antibody (IgG)
Epstein-Barr Virus Nuclear Antigen (EBNA) AB (IgG)
Epstein-Barr Virus Viral Capsid Antigen (VCA) AB (IgG)
Preferred Specimen
1 mL serum
Minimum Volume
0.8 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 1-5 days
Reference Range
See Laboratory Report
Clinical Significance
Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. VCA-IgM is typically detectable at clinical presentation, then declines to undetectable levels within a month in young children and within 3 months in other individuals.
VCA-IgG is typically detectable at clinical presentation and persists for life. IgG recognizing Early Antigen D appears within a month after clinical presentation and typically lasts only 3-4 months; persistently elevated levels suggest reactivation or persistence of EBV infection. EBNA IgG typically appears during convalescence (3-4 months after clinical presentation) and remains detectable for life.
VCA-IgG is typically detectable at clinical presentation and persists for life. IgG recognizing Early Antigen D appears within a month after clinical presentation and typically lasts only 3-4 months; persistently elevated levels suggest reactivation or persistence of EBV infection. EBNA IgG typically appears during convalescence (3-4 months after clinical presentation) and remains detectable for life.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153