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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Diazepam and Metabolite
Test Code90853
CPT Codes
80299
Includes
Diazepam, Nordiazepam, Diazepam and Nordiazepam
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Patient Preparation
Collect at trough concentration, i.e., immediately before the administration of the next dose
Minimum Volume
1 mL
Instructions
Use polypropylene tubes and ship on cold pack by overnight courier.
Transport Container
Polypropylene tubes
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 5 days
Frozen: 14 days
Refrigerated: 5 days
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST)
Methodology
Calculation (CALC) • Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues, Thurs, Sat; Report available: 3-5 days
Reference Range
Diazepam | See Laboratory Report |
Nordiazepam | See Laboratory Report |
Diazepam and Nordiazepam
Therapeutic | 100-1500 ng/mL |
Potentially toxic | >3000 ng/mL |
Clinical Significance
Therapeutic drug monitoring of anxiolytic drug. Nordiazepam is the active metabolite of the parent drug. Elimination half-life is 20-90 hours.
Performing Laboratory
Quest Diagnostics Nichols Institute-Valencia |
8407 Fallbrook Ave, Suite 100 |
West Hills, CA 91304-3226 |